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high-density oligonucleotide arrays platform  (Perlegen Sciences)

 
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    Perlegen Sciences high-density oligonucleotide arrays platform
    High Density Oligonucleotide Arrays Platform, supplied by Perlegen Sciences, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/high-density+oligonucleotide+array/high+density+oligonucleotide+arrays/pm39930364-169-36-34
    Average 90 stars, based on 1 article reviews
    high-density oligonucleotide arrays platform - by Bioz Stars, 2026-10
    90/100 stars

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    Related Articles

    Variant Assay:

    Article Title: Construction and characterization of a genomic BAC library for the Mus m. musculus mouse subspecies (PWD/Ph inbred strain)
    Article Snippet: Because of this unique feature, the PWD/Ph inbred strain has been nominated among 15 mouse strains, the genomes of which are being resequenced using high-density oligonucleotide array technology by Perlegen Sciences, Inc. [ ].

    Article Title: Headliners: Immunity: PCB Exposure Affects Antibody Response in Vaccinated Children
    Article Snippet: Kelly Frazer, principal investigator of the project and vice president of genomics at Perlegen Sciences, says, “We take these pieces of DNA and align them to A 26 VOLUME 115 | NUMBER 1 | January 2007 • Environmental Health Perspectives that reference sequence, and we look for differences.” To do that, the scientists used the same high-density oligonucleotide array technology that was used to discover common DNA variations in the human genome.

    Article Title: Pooled versus Individual Genotyping in a Breast Cancer Genome-wide Association Study
    Article Snippet: Consider a Δ value of 0.06, for allele frequency p varying from 0.1 to 0.5, the pooling error variance for allele frequency estimates using the Perlegen high-density oligonucleotide array falls into the range of 0.00068–0.0019, similar in magnitude to the pooling error reported in Macgregor (2007) using Affymatrix HindIII array.

    Article Title: Low LDL Cholesterol Is Not an Independent Risk Factor for Hepatic Steatosis.
    Article Snippet: Background Genetic mutations causing defective VLDL secretion and low LDL cholesterol are associated with hepatic steatosis and nonalcoholic fatty liver disease (NAFLD).. Aims Determine if low LDL cholesterol (< 5th percentile) was an independent predictor of hepatic steatosis.. Methods Secondary data analysis of the Dallas Heart study (an urban, multiethnic, probability-based sample), we defined hepatic steatosis utilizing intrahepatic triglyceride (IHTG) analyzed using magnetic resonance spectroscopy in conjunction and available demographic, serological and genetic information.

    Sequencing:

    Article Title: Construction and characterization of a genomic BAC library for the Mus m. musculus mouse subspecies (PWD/Ph inbred strain)
    Article Snippet: Because of this unique feature, the PWD/Ph inbred strain has been nominated among 15 mouse strains, the genomes of which are being resequenced using high-density oligonucleotide array technology by Perlegen Sciences, Inc. [ ].

    Article Title: Headliners: Immunity: PCB Exposure Affects Antibody Response in Vaccinated Children
    Article Snippet: Kelly Frazer, principal investigator of the project and vice president of genomics at Perlegen Sciences, says, “We take these pieces of DNA and align them to A 26 VOLUME 115 | NUMBER 1 | January 2007 • Environmental Health Perspectives that reference sequence, and we look for differences.” To do that, the scientists used the same high-density oligonucleotide array technology that was used to discover common DNA variations in the human genome.

    Article Title: Pooled versus Individual Genotyping in a Breast Cancer Genome-wide Association Study
    Article Snippet: Consider a Δ value of 0.06, for allele frequency p varying from 0.1 to 0.5, the pooling error variance for allele frequency estimates using the Perlegen high-density oligonucleotide array falls into the range of 0.00068–0.0019, similar in magnitude to the pooling error reported in Macgregor (2007) using Affymatrix HindIII array.

    Article Title: Low LDL Cholesterol Is Not an Independent Risk Factor for Hepatic Steatosis.
    Article Snippet: Background Genetic mutations causing defective VLDL secretion and low LDL cholesterol are associated with hepatic steatosis and nonalcoholic fatty liver disease (NAFLD).. Aims Determine if low LDL cholesterol (< 5th percentile) was an independent predictor of hepatic steatosis.. Methods Secondary data analysis of the Dallas Heart study (an urban, multiethnic, probability-based sample), we defined hepatic steatosis utilizing intrahepatic triglyceride (IHTG) analyzed using magnetic resonance spectroscopy in conjunction and available demographic, serological and genetic information.



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    Comparison of BCKDK gene expression between young and old age groups in Male ( A ) and Female ( B ) groups. Skeletal muscle biopsies of the vastus lateralis were obtained from human participants and gene expression was analyzed using Affymetrix (Santa Clara, CA, USA) HG-U133A and HF-U133B high-density oligonucleotide arrays. The data for ( A ) were retrieved from GEO dataset uploaded by Welle et al. GEO ID 1592758) ( n = 7–8) . Identical experimental procedures were used to assess female gene expression. This data from ( B ) were retrieved from GEO dataset uploaded by Welle et al. (GEO ID 3242858) significance determined by GEO2R adjusted * p -value = 0.0148 ( n = 7–8) .

    Journal: International Journal of Molecular Sciences

    Article Title: The Role of Branched Chain Ketoacid Dehydrogenase Kinase (BCKDK) in Skeletal Muscle Biology and Pathogenesis

    doi: 10.3390/ijms25147601

    Figure Lengend Snippet: Comparison of BCKDK gene expression between young and old age groups in Male ( A ) and Female ( B ) groups. Skeletal muscle biopsies of the vastus lateralis were obtained from human participants and gene expression was analyzed using Affymetrix (Santa Clara, CA, USA) HG-U133A and HF-U133B high-density oligonucleotide arrays. The data for ( A ) were retrieved from GEO dataset uploaded by Welle et al. GEO ID 1592758) ( n = 7–8) . Identical experimental procedures were used to assess female gene expression. This data from ( B ) were retrieved from GEO dataset uploaded by Welle et al. (GEO ID 3242858) significance determined by GEO2R adjusted * p -value = 0.0148 ( n = 7–8) .

    Article Snippet: The skeletal muscle samples were taken from the vastus lateralis, and gene expression analysis was conducted using high-density oligonucleotide arrays (Affymetrix HG-U133A and HF-U133B).

    Techniques: Comparison, Expressing

    Details of the GEO dataset study designs used to examine BCKDK gene expression in different models.

    Journal: International Journal of Molecular Sciences

    Article Title: The Role of Branched Chain Ketoacid Dehydrogenase Kinase (BCKDK) in Skeletal Muscle Biology and Pathogenesis

    doi: 10.3390/ijms25147601

    Figure Lengend Snippet: Details of the GEO dataset study designs used to examine BCKDK gene expression in different models.

    Article Snippet: The skeletal muscle samples were taken from the vastus lateralis, and gene expression analysis was conducted using high-density oligonucleotide arrays (Affymetrix HG-U133A and HF-U133B).

    Techniques: Expressing, Reverse Transcription, Isolation, Control, Cell Culture, Concentration Assay, DNA Methylation Assay, Activity Assay, In Vitro, Flow Cytometry, Confocal Microscopy, Knock-Out